Postdoctoral Scientist – Stem Cell Biology at Paterson Institute for Cancer Research UK
A three year position, is available in the laboratory of Dr Georges Lacaud to study the molecular and cellular mechanisms of early haematopoietic development. In this context, we are focusing on the function of the transcription factor AML1/Runx1, a master regulator of haematopoietic development but also a frequent target of gene rearrangements and mutations in human leukemia. The in vitro differentiation system based on mouse embryonic stem (ES) cells and in vivo approaches will be used. Our ultimate goal is to use either ES cell differentiation or epigenetic reprogramming to generate transplantable blood cell populations. Selected references: Lancrin et al., (2009) Nature. Sroczynska et al.,(2009) Blood.
The successful applicant should have a PhD in cellular biology or molecular biology. A background in haematopoiesis, immunology, leukaemogenesis or developmental biology is desirable but not required.
Informal enquiries should be directed to Dr Georges Lacaud glacaud@picr.man.ac.uk
The Paterson Institute is a leading cancer centre of excellence core-funded by Cancer Research UK and is an Institute of The University of Manchester. Salary in the range of £25,500 – £38,000 dependent upon qualifications and experience.
To apply for this position please complete an equal opportunities form and submit along with a CV to jobs@picr.man.ac.uk quoting the reference number above. For applicants who are unable to download this information from our website, please contact HR department on 0161 446 3231, email: jobs@picr.man.ac.uk to have this information sent by post.
Closing date: 6th May 2011
